Get it out!
When you have things bottled up inside of you, get them out!
The word disease is exact; DIS Ease. Sickness of the heart, mind or body many times starts with emotions. Emotions are the "feelings" that cause people to make life-altering decisions and have literally run the world at times. They cause people to dream, to relocate and even in the worse scenarios, to kill. If these emotions are so powerful, allowing them to stay trapped inside of your body can have destructive results.
If you are feeling down or overwhelmed I suggest that you express somehow. Give yourself the time to write a song, to paint a painting, craft or arrange a bouquet. Even if you are not artistic you can journal or write a letter to someone without the intention of sending it. No matter what you do, you must get the emotions out of you. When your body carries this around, you will begin to see the affects. Specifically, negative emotions are often the root of stress related diseases like anxiety, depression and even many physical ailments as well.